Proper and regular maintenance of the Evolution 4300 dissolution sampler is necessary to maintain proper performance and to maximize uptime. In this edition of Disteknique, we will detail the required cleaning of the system (especially after usage of surfactant-based media).
The EVO 4300 has a built-in cleaning function – System Wash. This function processes 20mL of wash solution through each channel, into the recycle bin, and then expelled via the replacement lines. Following up this action with an EMPTY action, will force air through the lines to remove any residual cleaning solution.
A very simple cleaning procedure can be accomplished as follows (and this can be executed through the QUICK ACTION COMMANDS):
- Remove any and all filters, filter adapters, etc. from the sample probes on the side of the pump to be cleaned (A, B, or both).
- Place the sample probes into DI Water (41° C recommended) – make sure to have at least 1L of cleaning solution per probe (i.e. a 6-channel system would require 20mL of wash media).
- Place the replacement lines into a waste receptacle.
- Execute a SYSTEM WASH
- For more difficult or “sticky” products 10% methanol or 10% isopropanol and DI water solution can be used. Place the sample probes into a beaker of the organic solution, and execute a SYSTEM WASH
- Repeat steps 2-3 three additional times with DI water to remove any left-over organic solvent or surfactant media.
- Execute an EMPTY to clear any residual cleaning solution from the lines.
- Remove the sample probes from the beaker, and let air dry.
Cleaning the EVO 4300 is a simple process that if performed regularly and frequently will help to ensure proper functioning of the system.